The FDA recently approved the cellular rejuvenation therapy ER-100 for human clinical trials. While vision is the first target, it could have applications for a variety of age-related disease. A longevity startup has dosed its first patient with a drug to reverse age-related sight loss. Life Biosciences is testing its ER-100 drug, which the company claims has restored vision in monkeys, for safety and side effects in a study of around 18 adults over the next year. It will be targeting patients with glaucoma and NAION, two conditions that cause damage to crucial cells in the optic nerve, which transmits visual information from the back of the eye to the brain.

Use this WIRED-exclusive coupon code to get the best deal on this high-design machine and biodegradable pods. If I could only have one pod coffee maker for the rest of time, it would be the Bruvi BV-01 (an 8/10 WIRED Review). It's the pod coffee maker against which I compare every other pod coffee maker. The one to beat, and no competition has come close to taking the crown. It's what I use when I'm not testing a new coffee maker for research.

Amid ongoing economic anxieties, BLK and other companies are giving away basic essentials to appeal to the public. While Gen Z catches a lot of flack for being single, or even antisocial, there's a brutal economic reality underscoring why some people aren't going out: They simply don't have the disposable income . Dating apps, already struggling to maintain user bases due to enshittification and a lack of quality matches, are contending with this affordability crisis. In a dystopian sign of the times, BLK, the app for Black singles, announced on Wednesday that it is giving away free gas in an attempt to incentivize people to go on dates. As part of the promotion, BLK is providing $500 gas gift cards to 10 people who download the app and tag three friends in the campaign post across its social channels.

These Robots Are Making Meals for a Nonprofit in San Francisco's Tenderloin A nonprofit in the city's most troubled district has turned to robotic meal prep tech to make up for a dearth of human volunteers. Project Open Hand, a nonprofit founded in 1985 by local grandmother and HIV-awareness advocate Ruth Brinker, prepares and packages meals to meet the diverse nutritional requirements of people who need them. The effort began in response to the AIDS crisis, but the nonprofit has since expanded the meals it makes for people with conditions such as heart disease, diabetes, or chronic kidney disease. But it takes many people to make these meals, and Project Open Hand has struggled to entice volunteers to help fill the meal kits. The organization is housed in a four-story building in San Francisco's Tenderloin district.

Instead of clicking on a bunch of random website links, I was reading an AI summary positioned at the top of my search results and sometimes clicking through to double-check the accuracy of the output. The next evolution of Search that Google is building asks for even less active participation from users. You're really the most involved at the start of the journey, and that's it. You tell the agents what you want to know, and they do the clicking and even calling on your behalf. Rather than you going off on some online adventure, it's the agent that's hoovering up anything it can find and bouncing between different sites.

Mira Murati Wants Her AI to'Keep Humans in the Loop' The Thinking Machines Lab founder and former CTO of OpenAI tells WIRED she isn't interested in automating people out of jobs. Instead, she's building AI that can collaborate. Mira Murati still wants to build AI superintelligence. But the ex-CTO of OpenAI sees human intelligence as a critical part of the equation. At a time of rising worry over AI eliminating jobs and increasing the power of few big companies, Murati's startup, Thinking Machines Lab, offers a radically different vision of the technology.

The plaintiffs and defense have rested their cases, as well as their rear ends. The final stragglers testified on Wednesday in the trial. The witnesses generated few waves, aside from the revelation that Microsoft has so far spent over $100 billion on its partnership with OpenAI . Rather than focus on that, I wanted to bring you a candid observation that my colleague Maxwell Zeff and I can't stop talking about after spending nearly three weeks watching the trial. The courtroom is littered with butt cushions.

A new collaboration with Alphabet's Wing will only deliver sandwiches. It demonstrates the tricky parts of taking to the sky. Starting today, eager customers of the US pizza restaurant chain Papa Johns living in one corner of southern North Carolina will have the opportunity to receive their food from the sky, thanks to a new collaboration with Alphabet's drone company, Wing . But Papa Johns' signature pizzas won't be on offer. Instead, drone-loving North Carolinians will have to choose between three kinds of sandwiches, a newer product for the fast-food chain: Philly cheesesteak, chicken bacon ranch, or steak and mushroom varieties.

What to Know About Sony's $7.85 Million PlayStation Settlement Are you eligible for a payout? Probably, but it might take a while and will likely be pretty small. Sony, owner of the PlayStation brand, has been accused of antitrust practices. The lawsuit was originally settled in 2024 but was rejected twice during the approval process. Last week, a judge approved a preliminary reopening of the settlement.

It's an expensive time to fly. These tips can help lighten the load on your wallet. As a general rule, global instability leads to higher prices, and boy, is the world a doozy right now . Airfare hasn't escaped the tumult: US airfares are up 14.9 percent compared to a year ago, according to NerdWallet, largely due to fuel price spikes linked to disruptions in the Strait of Hormuz caused by blockages, bombs, and blockades. While the medium-term outlook for the airline business isn't great, there are still a few smart and tricky ways to save a little money when flying this summer.